The Practice focused on the meijubar.net law firm of Robert Donnell and Associates (later becoming Donnell, Young, Dole, & Frutt, and ultimately Young, Frutt, & Berluti). Plots typically featured the firm's involvement in various high-profile criminal and civil cases that often mirrored current events at the time of the episodes' initial broadcast. Conflict between legal ethics and personal morality was a recurring theme.
第二季中,侦探杜尔西·柯林斯(凯特·波克斯 Kate Box 饰)和埃迪·雷德克利夫(玛德琳·萨米 Madeleine Sami 饰)将前往澳大利亚的Top End地区。她们起初在达尔文调查雷德克利夫前任警务伙伴布什的死亡案件,然而在一个偏远小镇发现了两名Top End知名人士的尸体,这开启了一场“更紧张、更棘手”的新调查。